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عمومی::
ترایال بین المللی آنوریسم ساب آراکنویید
high as 70%.153 The risk of rebleeding is the highest within the first 24 hours (4%-15%) after the initial bleed, remains elevated for the next 2 to 4 weeks (1%-2% per day), then eventually decreases to 2% to 4% annually after the first 6 months.154-156 To reduce the risk of rebleeding, guidelines recommend securing the ruptured aneurysm by surgical clipping or endovascular coiling as soon as possible and ide- ally within the first 24 hours after symptom onset.157-159 Since the publication of the International Subarachnoid Aneurysm Trial, endovascular coiling is the recommended treatment when the location, size, and morphology of aneurysm are favorable.
International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascu- lar coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial.
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascu- lar coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, sei- zures, rebleeding, subgroups, and aneurysm occlusion.
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